Molecular Formula | C24H36O4 |
Molar Mass | 388.54 |
Density | 1.120±0.06 g/cm3(Predicted) |
Melting Point | 152 °C |
Boling Point | 544.7±25.0 °C(Predicted) |
pKa | 4.76±0.10(Predicted) |
Storage Condition | 2-8°C |
Reference Show more | 1. [IF=6.558] Yan Cao et al."Widely quasi-quantitative analysis enables temporal bile acids-targeted metabolomics in rat after oral administration of ursodeoxycholic acid."ANALYTICA CHIMICA ACTA. 2022 Jun;1212:339885 |
3,7-Diketocholic acid (3,7-DIKETO-5BETA-CHOLAN-24-OIC ACID) is a type of bile compound.
Nature:
-Appearance: Colorless crystals or white crystalline powder.
-Solubility: Easily soluble in alcohols and organic solvents, slightly soluble in water.
Usage:
-Treatment of gallstones: 3,7-diketocholic acid can promote the excretion of bile acids by adjusting the balance between cholesterol and bile acids, thereby reducing the formation and stagnation of gallstones.
-Bile acid analysis: As a representative compound of bile acids, 3,7-diketocholic acid is commonly used for qualitative and quantitative analysis of bile acids.
Method:
The preparation of 3,7-diketocholic acid usually adopts a synthetic route. One common preparation method is obtained through the oxidation reaction of cholesterol, and specific operations and reaction conditions can refer to relevant literature.
Security information:
-3,7-Diketocholic acid can irritate the eyes and skin, and appropriate protective measures should be taken when in contact.
-During use and storage, contact with oxidants should be avoided to prevent fire or explosion.